Fortæl dine venner om denne vare:
In-cell Approaches in Electron Paramagnetic Resonance Spectroscopy: In-cell Approaches in Electron Paramagnetic Resonance Spectroscopy to Study Conformations of Dna G-quadruplexes
Mykhailo Azarkh
Bestilles fra fjernlager
In-cell Approaches in Electron Paramagnetic Resonance Spectroscopy: In-cell Approaches in Electron Paramagnetic Resonance Spectroscopy to Study Conformations of Dna G-quadruplexes
Mykhailo Azarkh
Double electron electron resonance (DEER) is an EPR technique which allows for distance measurements on the nanometer scale. Here, EPR-based distance measurements were extended to in-cell applications. From evaluation of nitroxides for experiments in intracellular environment of Xenopus laevis oocytes and through proof-of-principle experiments optimal parameters for performing in-cell DEER were found. On the example of G-quadruplexes formed by oligomers of human telomeric DNA, DEER was shown to be applicable for structural identification of biological objects under their native conditions.
Medie | Bøger Paperback Bog (Bog med blødt omslag og limet ryg) |
Udgivet | 10. august 2012 |
ISBN13 | 9783838134406 |
Forlag | Südwestdeutscher Verlag für Hochschulsch |
Antal sider | 152 |
Mål | 150 × 9 × 225 mm · 231 g |
Sprog | Engelsk |
Se alt med Mykhailo Azarkh ( f.eks. Paperback Bog )